Description
Anticoccidial
Composition
Kimia Cluzine® belongs to the sulfonamide group and acts as a PABA antagonist (a folic acid precursor) in coccidia protozoa and bacteria. Since folic acid is essential for the survival and reproduction of these organisms, inhibition of its synthesis disrupts their life cycle and leads to cessation of growth.
Sulfaquinoxaline is particularly effective in inhibiting the second schizont stage in coccidiosis.
Indications
Kimia Cluzine® is used for the treatment of coccidiosis caused by various Eimeria species, including:
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Eimeria necatrix, maxima, acervulina, mitis, tenella, brunetti, praecox, adenoeides, meleagrimitis
It is also indicated for the treatment of:
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Salmonellosis caused by Salmonella gallinarum, pullorum, enteritidis, and typhimurium
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Pasteurellosis (fowl cholera)
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Infectious coryza caused by Haemophilus paragallinarum
Dosage and Administration
Standard treatment of coccidiosis
Poultry, turkeys, guinea fowl, and rabbits:
50 mg of active sulfaquinoxaline per kg of body weight per day, equivalent to
100 g of Kimia Cluzine® per 100 liters of drinking water for 3 consecutive days.
⚠ Note: In infections caused by Eimeria tenella and Eimeria necatrix, increase the dose to 100 g per 50 liters of drinking water.
Intermittent treatment regimen
Dissolve 100 g of Kimia Cluzine® in 100 liters of drinking water and administer on:
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Days 1, 3, 5, 7, 9, or alternatively
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Days 1, 2, 5, 6, 9 (highly effective regimen)
In outbreak situations, repeat treatment at 3 and 5 weeks of age for 2–3 consecutive days.
Additional Guidelines
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Feed administration:
20 sachets (2 kg of sulfaquinoxaline 30%) per ton of feed -
Salmonellosis and pasteurellosis:
100–200 g of Kimia Cluzine® per 100 liters of drinking water for at least 5 days -
Always pre-dissolve a small amount of the product in water or feed before adding it to the main drinking water source or feed tank.
The medicated water must be the sole source of drinking water during treatment.
Sheep and Goats
Dissolve one 100-g sachet in 10 liters of water and administer 12 mL per 10 kg of body weight.
Contraindications
None.
Withdrawal Period
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Broiler chickens (meat): 14 days after last administration
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Laying hens (eggs): 11 days after last administration
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Turkeys (meat): 14 days after last administration
Precautions
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Use the prepared solution immediately after preparation.
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In case of hemorrhage due to overdose, administer Vitamin K to correct the condition.
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During and after treatment, supplementation with vitamins and disinfection of cages, especially in laying flocks, is recommended and beneficial.
