{"id":2744,"date":"2025-11-05T06:38:29","date_gmt":"2025-11-05T06:38:29","guid":{"rendered":"https:\/\/kf-group.ir\/?page_id=2744"},"modified":"2025-12-21T19:48:44","modified_gmt":"2025-12-21T19:48:44","slug":"why-kimiafaam","status":"publish","type":"page","link":"https:\/\/kf-group.ir\/en\/why-kimiafaam\/","title":{"rendered":"Why Kimiafaam"},"content":{"rendered":"\t\t
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Why Kimiafaam?<\/h2>\t\t\t\t<\/div>\n\t\t
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From the very beginning of its operations, Kimiafaam Pharmaceutical Group established its Research and Development (R&D) department based on a strong belief in the importance of research and the necessity of advancement in the industry. In 2006 (1385 in the Iranian calendar), the R&D group successfully obtained an independent R&D license from the Ministry of Industry and Mines.<\/p>

Experts in various fields\u2014including veterinary science, pharmacy, chemistry, microbiology, and others\u2014are actively working in this department. In addition, the group benefits from the collaboration and consultation of prominent university professors and reputable scientific institutions. The R&D department operates with a vision of creating a reliable link between the pharmaceutical industry, various related industries, universities, and scientific centers.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Quality Control Laboratory<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Physical Control Laboratory<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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As part of the quality control division of Kimiafaam Pharmaceutical Company, this unit is responsible for physical inspection of packaging materials\u2014including bottles, pouches, labels, and all packaging components\u2014based on established checklists. It is also responsible for sampling raw materials and performing initial quality evaluations of these materials.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Microbiology Laboratory<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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This laboratory is responsible for monitoring environmental and microbial conditions across various production sections. Activities include microbial control of water, personnel, raw materials, packaging equipment, products, and the determination of vitamin and antibiotic potency. These procedures are performed using advanced equipment such as autoclaves, ovens, laminar flow hoods, UV devices, various incubators, and spectrophotometers, following the latest pharmacopeia methods.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Stability Laboratory<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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This unit is responsible for monitoring the stability of all manufactured products periodically and systematically for up to one year after their expiration date. It also handles quality control of products based on received complaints and reports, as well as Post-Marketing Quality Control (PMQC) of medicines in the market.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Stability Unit<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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In this unit, samples of final products are stored for up to one year after their expiration date, under appropriate temperature and humidity conditions, following WHO guidelines and pharmacopeial standards.<\/p>

Accelerated stability studies are also conducted in this unit using germinators of various capacities.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Chemistry Laboratory<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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This section performs a wide range of analyses on raw materials and finished products. All tests are conducted according to validated Standard Operating Procedures (SOPs) prepared based on the latest pharmaceutical references, including the United States Pharmacopeia (USP), European Pharmacopeia (EP), and British Pharmacopeia (BP).<\/p>

These analyses are carried out using advanced equipment such as HPLC, UV, GC, potentiometers, FTIR, atomic absorption devices, melting point apparatus, distillation columns, and other routine laboratory instruments.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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In-Process Quality Control Laboratory (IPQC)<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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This laboratory is responsible for supervising all production sections, including manufacturing and packaging stages. Its purpose is to ensure the implementation of GMP regulations throughout every phase of production\u2014from raw-material weighing to final product packaging.<\/p>

By equipping this laboratory with instruments such as conductometers, pH meters, viscometers, and others, real-time qualitative and quantitative evaluation of products becomes possible during production within the manufacturing halls.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Formulation<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Pharmaceutical formulation plays a crucial role in the effectiveness of any medication. Drugs are rarely administered as pure chemical substances and are almost always delivered as formulated products or dosage forms. To achieve this, formulations may range from relatively simple solutions to complex drug-delivery systems, using suitable additives or excipients. These additives, together with other components, enable dissolution, suspension, thickening, protection, and ultimately the formation of various pharmaceutical products and dosage forms.<\/p>

To ensure product quality, numerous characteristics are required, including chemical and physical stability, appropriate protection against microbial contamination when necessary, uniformity of drug dosage, user acceptability, and proper packaging and labeling.<\/p>

It is essential to recognize the differences that may exist between formulations that appear similar and the possible reasons behind these differences. It is now clear that formulation can influence the therapeutic performance of a drug. For this reason, increasing attention in recent years has been directed toward minimizing differences in bioavailability, especially for chemically equivalent products.<\/p>

To optimize the bioavailability of an active substance, it is often necessary to carefully select the most suitable chemical form of the drug. Such decisions must consider required solubility, particle size, and physical form of the drug, as well as the excipients used in producing the pharmaceutical product. Proper manufacturing processes and packaging also play important roles.<\/p>

Kimiafaam pharmaceutical products, in addition to utilizing modern formulations (from companies such as Hipra, Krka, and Janssen), are manufactured using raw materials sourced from reputable European suppliers and with the highest possible concentration of active ingredients. In Kimiafaam’s multivitamin solutions, a solvent called Cremophor is used, which provides exceptional solubility for these products.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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